A new treatment for cholesteas could make it easier for women to conceive without suffering painful ectopic pregnancies and other unwanted pregnancies.
Cholestatic contraception is a pill that can prevent ectopic or ectopic fertilization of eggs or sperm.
The pills can be used for the first time after conception or as part of a long-term contraceptive regimen, and can be taken as a daily pill, two times a day, or in three doses.
Researchers have known about a new drug called cholestyramine, or COC, for a decade, but until now, no treatment for ectopic parenthood was known to prevent the pregnancies that were a mainstay of the condition.
Chlorogenic acid, which is a naturally occurring compound found in cholestation, also acts as an antifungal, preventing fungus growth in the cervix, a common cause of ectopic childbirth.
Researchers at the University of New South Wales in Sydney and the University in California have now published a paper on the drug in the journal PLOS ONE.
“The first time we tested COC for ectoparous pregnancy, we found that it was able to prevent fertilization, but it didn’t prevent ectoparyotrophic pregnancies, which could be fatal,” said lead researcher Dr David Gomes, from the University’s School of Pharmacy and Health Sciences.
“This drug is a very effective treatment for those women that have had a serious ectopic problem, but we wanted to make sure we could safely treat those who didn’t need to have a pregnancy.”
So the next step is to try to find a safe, effective and long-lasting way of preventing ectopic and ectopic-like pregnancies.
“There are still many unanswered questions about how COC works, so this is the next important step in our research.”COC works by disrupting a chemical pathway in the lining of the womb, preventing fertilization.
It has a short half-life, meaning that it lasts only two weeks, which means it would be able to be administered at the same time that an egg or sperm is fertilized.
The researchers say it could also be used to treat other types of ectoparity.
“One of the reasons why choliestasis is so important is because it’s caused by a chemical imbalance in the reproductive system, so it’s not just a one-off pregnancy,” Dr Gomes said.
“It can happen to a lot of women in their 20s and 30s, and it can lead to infertility, ectopy, ectopias, and other reproductive problems.”
The drug could be tested in women in Australia and New Zealand, where the drug is currently approved.
It is expected to be available for sale within a year.